From polymorphism to personalized medicine overthelast20yearsgenome wideassociationstudiesgwashaverevealedagreat deal about the genetic basis of a wide range of complex diseases and they will. Genome wide association studies from polymorphism to personalized medicine responsibility edited by krishnarao appasani geneexpression systems inc forewords by stephen w scherer universtiy of toronto canada and peter m visscher university of queensland australia. Genome wide association studies from polymorphism to personalized medicine edited by krishnarao appasani summarizes most elegantly the contributions of gwas as a major discovery tool linking gwas has transformed the genetic landscape in complex disease and has informed us more about the genetic underpinnings of common diseases and . Nih the foundation for the national institutes of health pfizer global research development and others have formed a public private partnership the genetic association information network gain to fund genome wide association studies. Despite large public investments in genome wide association studies of common human diseases so far few gene discoveries have led to applications for clinical medicine or public health genome wide association studies in the context of clinical trials of drug safety and efficacy may be quicker to
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