Calcium and myocardial protection glen j kowalchuk md and richard w nesto md painful and asymptomatk ischemia has been asso ciated with left ventricular dysfunction an impor tant variable related to survival in patients with coronary artery disease. Together with beta blockers and nitrates calcium channel antagonist drugs are one of the standard treatments of hypertension this reference aims to present clinicians with the facts required to read more. Request pdf on researchgate calcium antagonists and myocardial protection painful and asymptomatic ischemia has been associated with left ventricular dysfunction an important variable related . The calcium antagonists have specific value in variant angina by causing peripheral vasodilatation they are also effective hypotensive agents and do not cause reflex tachycardia in chronic use their value in hypertrophic cardiomyopathy and in the protection of ischaemic myocardium remains to be proven. Calcium antagonists have multiple mechanisms whereby they are able to protect against myocardial ischaemia key words calcium antagonists angina myocardial protection safety efficacy post infarct introduction calcium channel antagonists are certainly able to provide
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